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In 1952, Christine Jorgensen became a global sensation as the first widely publicized person to undergo sex reassignment surgery, paving the way for public discussions on gender-affirming care. Marsha P. Johnson

The woman looked up. Her face was a map of fine lines and older surgeries—the telltale softness around the jaw, the elegant width of her shoulders. She was maybe seventy. Her eyes, however, were twenty.

: Historically, Jewish law has recognized up to eight gender categories [29]. Other examples include the burrnesha in Albania, women who live as men [29], and "third gender" classifications in various Eastern cultures [6].