The closest official version to a portable experience is the . It allows you to create and edit diagrams directly in a browser without installing software on your machine.
: By storing files in OneDrive for Business , you can access your latest diagrams from any workstation without needing a physical storage device. Portable Alternatives
to create custom, "lighter" installations for specific environments, though this still requires a setup process. Top Portable & Web Alternatives
Here is a detailed breakdown of why the "Portable" version is problematic and the best legitimate alternatives for users on the go.
Microsoft does not offer an official "portable" version of Visio designed to run from a USB drive without installation. However, you can achieve a similar "work anywhere" experience using or authorized cloud-based solutions.